The caudate: a key node in the neuronal network imbalance of insomnia?

  title={The caudate: a key node in the neuronal network imbalance of insomnia?},
  author={Diederick Stoffers and Ellemarije Altena and Ysbrand D. van der Werf and Ernesto J. Sanz-Arigita and Thom Voorn and Rebecca G. Astill and Rob L. M. Strijers and D{\'e} Waterman and Eus J. W. Van Someren},
  booktitle={Brain : a journal of neurology},
Insomnia is prevalent, severe and partially heritable. Unfortunately, its neuronal correlates remain enigmatic, hampering the development of mechanistic models and rational treatments. Consistently reported impairments concern fragmented sleep, hyper-arousal and executive dysfunction. Because fronto-striatal networks could well play a role in sleep, arousal regulation and executive functioning, the present series of studies used an executive task to evaluate fronto-striatal functioning in… CONTINUE READING
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