The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine.

@article{Yamamoto1999TheCH,
  title={The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine.},
  author={Hiroyuki Yamamoto and Ken-Ichi Miyamoto and Baitao Li and Yutaka Taketani and Motoo Kitano and Yusuke Inoue and Kyoko Morita and John Wesley Pike and Eiji Takeda},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1999},
  volume={14 2},
  pages={240-7}
}
The actions of 1,25-dihydroxyvitamin D3 (1,25(OH)2 D3) are mediated through the nuclear vitamin D receptor (VDR). The regulation of VDR abundance plays an important role in determining the magnitude of the target cell response to 1,25(OH)2D3. The major physiological activity of 1,25(OH)2D3 is the regulation of calcium absorption in the small intestine, and the level of VDR is an important factor in this regulation. However, the characterization of VDR gene expression in the small intestine… CONTINUE READING