The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin.

  title={The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin.},
  author={K. Palczewski and P. Hargrave and J. H. Mcdowell and T. Ingebritsen},
  volume={28 2},
  • K. Palczewski, P. Hargrave, +1 author T. Ingebritsen
  • Published 1989
  • Chemistry, Medicine
  • Biochemistry
  • Rod cell outer segments were found to contain a protein phosphatase activity toward phosphoopsin with properties very similar to those of protein phosphatase 1 or 2A. The opsin phosphatase activity was stable to ethanol precipitation, had a Mr of 35,000-38,000 as determined by gel filtration, and was not dependent on divalent cations for activity. The chromatographic properties on DEAE-cellulose of the rod outer segment protein phosphatase were also similar to those reported for protein… CONTINUE READING
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