The catalase inhibitor sodium azide reduces ethanol-induced locomotor activity.

@article{SanchisSegura1999TheCI,
  title={The catalase inhibitor sodium azide reduces ethanol-induced locomotor activity.},
  author={Carles Sanchis-Segura and Marta Miquel and Juan Guillermo Mu{\~n}oz Correa and Carlos M. G. Aragon},
  journal={Alcohol},
  year={1999},
  volume={19 1},
  pages={
          37-42
        }
}
The involvement of brain catalase in modulating the psychopharmacological effects of ethanol was investigated by examining ethanol-induced locomotor activity in sodium azide-treated mice. Mice were pretreated with i.p. injections of the catalase inhibitor sodium azide (5, 10, or 15 mg/kg) or saline. Following this treatment, animals received i.p. injections of ethanol (0.0, 1.6, 2.4, or 3.2 g/kg). Ten minutes after ethanol administration, locomotor activity was recorded during a 10-min testing… CONTINUE READING
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