The catabolite control protein CcpA binds to Pmga and influences expression of the virulence regulator Mga in the Group A streptococcus.

@article{Almengor2007TheCC,
  title={The catabolite control protein CcpA binds to Pmga and influences expression of the virulence regulator Mga in the Group A streptococcus.},
  author={Audry C Almengor and Traci L. Kinkel and Stephanie J Day and Kevin S McIver},
  journal={Journal of bacteriology},
  year={2007},
  volume={189 23},
  pages={8405-16}
}
Carbon catabolite repression (CCR) allows bacteria to alter metabolism in response to the availability of specific sugar sources, and increasing evidence suggests that CCR is involved in regulating virulence gene expression in many pathogens. A scan of the M1 SF370 group A streptococcus (GAS) genome using a Bacillus subtilis consensus identified a number of potential catabolite-responsive elements (cre) important for binding by the catabolite control protein A (CcpA), a mediator of CCR in gram… CONTINUE READING

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