The cardioprotection of calcitonin gene-related peptide-mediated preconditioning.

@article{Li2002TheCO,
  title={The cardioprotection of calcitonin gene-related peptide-mediated preconditioning.},
  author={Yuanjian Li and Jun Peng},
  journal={European journal of pharmacology},
  year={2002},
  volume={442 3},
  pages={173-7}
}
Preconditioning induced by brief ischemia or hyperthermia or some drugs shows two phases, early and delayed protection. The cardioprotection afforded by preconditioning is related to stimulation of endogenous mediators release. Calcitonin gene-related peptide (CGRP), a major transmitter of capsaicin-sensitive sensory nerves, has recently been shown to play an important role in mediation of the preconditioning induced by brief ischemia or hyperthermia or by some drugs, and alpha-CGRP seems to… CONTINUE READING

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