The cardiac troponin I gene is not associated with hypertrophic cardiomyopathy in patients from eastern Finland.

@article{Jskelinen1999TheCT,
  title={The cardiac troponin I gene is not associated with hypertrophic cardiomyopathy in patients from eastern Finland.},
  author={Pertti J{\"a}{\"a}skel{\"a}inen and Raija Miettinen and K Silvennoinen and Ilkka Vauhkonen and Markku Laakso and Johanna Kuusisto},
  journal={Journal of molecular and cellular cardiology},
  year={1999},
  volume={31 11},
  pages={2031-6}
}
Defects in seven genes encoding sarcomere proteins have been shown to cause hypertrophic cardiomyopathy. To date, only one study reporting defects in the cardiac troponin I gene associated with hypertrophic cardiomyopathy has been published, and the proportion of hypertrophic cardiomyopathy cases caused by defects in this gene is unknown. Therefore, the authors screened 37 unrelated Finnish patients with hypertrophic cardiomyopathy for variants in the cardiac troponin I gene. Exons 1-8 of the… CONTINUE READING