The cardiac renin-angiotensin system: conceptual, or a regulator of cardiac function?

@article{Dostal1999TheCR,
  title={The cardiac renin-angiotensin system: conceptual, or a regulator of cardiac function?},
  author={David E. Dostal and Kenneth M. Baker},
  journal={Circulation research},
  year={1999},
  volume={85 7},
  pages={643-50}
}
Angiotensin II, the effector peptide of the renin-angiotensin system, regulates cellular growth in response to developmental, physiological, and pathological processes. The identification of renin-angiotensin system components and angiotensin II receptors in cardiac tissue suggests the existence of an autocrine/paracrine system that has effects independent of angiotensin II derived from the circulatory system. To be functional, a local renin-angiotensin system should produce sufficient amounts… CONTINUE READING

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