The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.

@article{Koren2017TheCM,
  title={The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.},
  author={Lilach Koren and Uri Barash and Yaniv Zohar and Natan Karin and Ami Aronheim},
  journal={International journal of cardiology},
  year={2017},
  volume={228},
  pages={
          394-400
        }
}
RATIONAL Pressure overload induces adaptive and maladaptive cardiac remodeling processes in the heart. Part of the maladaptive process is the cross-talk between cardiomyocytes and macrophages which is dependent on the function of the Activating Transcription Factor 3, ATF3. Yet, the molecular mechanism involved in cardiomyocytes-macrophages communication leading to macrophages recruitment to the heart and cardiac maladaptive remodeling is currently unknown. METHODS AND RESULTS Isolated… CONTINUE READING
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SHOWING 1-10 OF 32 REFERENCES

I

  • L. Koren, D. Alishekevitz, O. Elhanani, A. Nevelsky, T. Hai
  • Kehat, et al., ATF3dependent cross-talk between…
  • 2015
Highly Influential
6 Excerpts

Themultifaceted functions of CXCL10 in cardiovascular disease, Biomed. Res

  • P. van den Borne, P. H. Quax, I. E. Hoefer, G. Pasterkamp
  • 2014
Highly Influential
5 Excerpts

N

  • M. Liu, S. Guo, J. M. Hibbert, V. Jain
  • Singh, N.O. Wilson, et al., CXCL10/IP-10 in…
  • 2011
Highly Influential
4 Excerpts

Q

  • T. Yang, Z. N. Li, G. Chen
  • Gu, X.H. Ni, Z.H. Zhao, et al., Increased levels…
  • 2014
1 Excerpt

R

  • Y. Zohar, G. Wildbaum, R. Novak, A. L. Salzman, M. Thelen
  • Alon, et al., CXCL11dependent induction of FOXP3…
  • 2014
2 Excerpts

Themultifaceted functions of CXCL 10 in cardiovascular disease

  • P. H. Quax P. van den Borne, I. E. Hoefer, G. Pasterkamp
  • Biomed . Res . Int .
  • 2014

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