The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase.

@article{Zahler1992TheCC,
  title={The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase.},
  author={Raphael S. Zahler and Michael Brines and Michael Kashgarian and Edward J. Benz and Maureen Gilmore-Hebert},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 1},
  pages={99-103}
}
The sodium pump is crucial for the function of the heart and of the cardiac conduction system, which initiates the heartbeat. The alpha (catalytic) subunit of this pump has three isoforms; the alpha 1 isoform is ubiquitous, but the alpha 2 and alpha 3 isoforms are localized to excitable tissue. Because rodent alpha 2 and alpha 3 isoforms are relatively… CONTINUE READING