The carcinogenicity of methoxyl derivatives of 4-aminoazobenzene: correlation between DNA adducts and genotoxicity.

@article{Kojima1994TheCO,
  title={The carcinogenicity of methoxyl derivatives of 4-aminoazobenzene: correlation between DNA adducts and genotoxicity.},
  author={Masayasu Kojima and Masakuni Degawa and Yuichi Hashimoto and Mariko Tada},
  journal={Environmental Health Perspectives},
  year={1994},
  volume={102},
  pages={191 - 194}
}
To elucidate the cause of the difference in genotoxic activity between carcinogenic 3-methoxy-4-aminoazobenzene (3-MeO-AAB) and noncarcinogenic 2-methoxy-4-aminoazobenzene (2-MeO-AAB), we analyzed DNA adducts in the livers of rats exposed to either of these chemicals and studied the resulting biologic potential with the aid of in vitro modified M13 phage… CONTINUE READING