The carboxyproxyl-derived spin trap (CP-H) is an appropriate detector-compound for oxidative stress
@article{Adam2010TheCS, title={The carboxyproxyl-derived spin trap (CP-H) is an appropriate detector-compound for oxidative stress}, author={S Adam and Hagen Loertzer and P. Fornara and H. J. Br{\"o}mme}, journal={Urological Research}, year={2010}, volume={38}, pages={179-186} }
Reperfusion of ischemic tissue disturbs the balance between reactive oxygen species (ROS) and the cellular antioxidative defense. This imbalance is known as oxidative stress. In this study the spin trap 3-carboxy-2,2,5,5-tetramethylpyrrolin-1-hydroxide (CP-H) with its ESR-detectable paramagnetic analogue 3-carboxy-2,2,5,5-tetramethylpyrrolin-1-oxyl (•CP) was analyzed in vitro and in vivo. In preliminary in vitro experiments we studied the interaction of CP-H with reactive compounds like…
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