The carboxyl terminus of myosin binding protein C (MyBP-C, C-protein) specifies incorporation into the A-band of striated muscle.

@article{Gilbert1996TheCT,
  title={The carboxyl terminus of myosin binding protein C (MyBP-C, C-protein) specifies incorporation into the A-band of striated muscle.},
  author={Robert Owen Gilbert and Michael G. Kelly and Tsutomu Mikawa and Donald A. Fischman},
  journal={Journal of cell science},
  year={1996},
  volume={109 ( Pt 1)},
  pages={101-11}
}
Myosin binding protein-C (MyBP-C), also known as C-protein, is a major constituent of the thick filaments of vertebrate striated muscles. The protein, approximately 130 kDa, consists of a series of 10 globular motifs (numbered I to X) each of approximately 90-100 amino acids, bearing resemblance to the C2-set of immunoglobins (Ig C2) and to the fibronectin type III (FnIII) motifs. Using pure preparations of myosin and MyBP-C, it has been demonstrated that the major myosin binding domain of MyBP… CONTINUE READING

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Antibodies: a Laboratory Manual

  • E. D. Harlow, D. Lane
  • 1988
Highly Influential
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