The carboxyl-half of the rotavirus nonstructural protein NS53 (NSP1) is not required for virus replication.

@article{Hua1994TheCO,
  title={The carboxyl-half of the rotavirus nonstructural protein NS53 (NSP1) is not required for virus replication.},
  author={Jack Hua and John T Patton},
  journal={Virology},
  year={1994},
  volume={198 2},
  pages={567-76}
}
The rotavirus nonstructural protein NS53 (NSVP1), the product of genome segment 5, possesses RNA-binding activity and contains a highly conserved cysteine-rich motif located in the amino-terminal half of the protein. The genome of the bovine rotavirus variant, brvA, lacks a normal segment 5 but includes a novel dsRNA (gene A) of approximately 2600 basepairs (bp) that contains segment 5-specific sequences (F. Hundley, B. Biryahwaho, M. Gow, and U. Desselberger, Virology 143, 88-103, 1985). To… CONTINUE READING

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