The capsule of bacillus anthracis, a review

  title={The capsule of bacillus anthracis, a review},
  author={Ezzell and Welkos},
  journal={Journal of applied microbiology},
  volume={87 2},
  • Ezzell, Welkos
  • Published 1999 in Journal of applied microbiology
The capsule of Bacillus anthracis, composed of poly-D-glutamic acid, serves as one of the principal virulence factors during anthrax infection. By virtue of its negative charge, the capsule is purported to inhibit host defence through inhibition of phagocytosis of the vegetative cells by macrophages. In conjunction with lethal toxin and oedema toxin, whose target cells include macrophages and neutrophils, respectively, the capsule allows virulent anthrax bacilli to grow virtually unimpeded in… CONTINUE READING

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