The capsaicin-sensitive afferent neuron in skeletal muscle is abnormal in heart failure.

@article{Smith2005TheCA,
  title={The capsaicin-sensitive afferent neuron in skeletal muscle is abnormal in heart failure.},
  author={Scott A. Smith and Maurice A Williams and Jere H. Mitchell and Pradeep P A Mammen and Mary G. Garry},
  journal={Circulation},
  year={2005},
  volume={111 16},
  pages={2056-65}
}
BACKGROUND In heart failure, the cardiovascular response to activation of the skeletal muscle exercise pressor reflex (EPR) is exaggerated. Group IV afferent neurons, primarily stimulated by the metabolic by-products of skeletal muscle work, contribute significantly to the EPR. Therefore, it was postulated that alterations in the activity of group IV… CONTINUE READING