The cap-to-tail guide to mRNA turnover

@article{Wilusz2001TheCG,
  title={The cap-to-tail guide to mRNA turnover},
  author={C. Wilusz and M. Wormington and S. Peltz},
  journal={Nature Reviews Molecular Cell Biology},
  year={2001},
  volume={2},
  pages={237-246}
}
The levels of cellular messenger RNA transcripts can be regulated by controlling the rate at which the mRNA decays. Because decay rates affect the expression of specific genes, they provide a cell with flexibility in effecting rapid change. Moreover, many clinically relevant mRNAs — including several encoding cytokines, growth factors and proto-oncogenes — are regulated by differential RNA stability. But what are the sequence elements and factors that control the half-lives of mRNAs? 
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