The cannabis withdrawal syndrome
@article{Budney2006TheCW, title={The cannabis withdrawal syndrome}, author={Alan J. Budney and John R Hughes}, journal={Current Opinion in Psychiatry}, year={2006}, volume={19}, pages={233–238} }
Purpose of review The demand for treatment for cannabis dependence has grown dramatically. The majority of the people who enter the treatment have difficulty in achieving and maintaining abstinence from cannabis. Understanding the impact of cannabis withdrawal syndrome on quit attempts is of obvious importance. Cannabis, however, has long been considered a ‘soft’ drug, and many continue to question whether one can truly become dependent on cannabis. Skepticism is typically focused on whether…
325 Citations
Clinical management of cannabis withdrawal
- Medicine, PsychologyAddiction
- 2021
The clinical significance of cannabis withdrawal is that its symptoms may precipitate relapse to cannabis use and complicated withdrawal may occur in people with concurrent mental health and polysubstance use.
The cannabis withdrawal syndrome: current insights
- Medicine, PsychologySubstance abuse and rehabilitation
- 2017
The cannabis withdrawal syndrome (CWS) is a criterion of cannabis use disorders (CUDs) (Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition) and cannabis dependence (ICD]-10 and the up-to-date ICD-11 Beta Draft is recommended to be expanded by physical CWS symptoms, the specification of CWS intensity and duration as well as gender effects.
Potential Pharmacotherapies for Cannabis Dependence
- Biology, Medicine
- 2010
This chapter reviews data from recent research on cannabinoids that may be relevant for the development of pharmacotherapies for cannabis dependence and assesses the effects of potential cannabis treatment medications on cannabinoid-related physiological, subjective, and reinforcing effects.
A Systematic Review of the Efficacy of Cannabinoid Agonist Replacement Therapy for Cannabis Withdrawal Symptoms
- Medicine, PsychologyCNS Drugs
- 2018
The findings demonstrate that the use of dronabinol, nabilone, or nabiximols, either alone or in combination with other drugs, shows promise in reducing cannabis withdrawal symptoms, probably with a dose-dependent effect.
Treatment of Cannabis Withdrawal Syndrome Using Cognitive-Behavioral Therapy and Relapse Prevention for Cannabis Dependence
- Psychology, Medicine
- 2010
It is suggested that weekly sessions of group cognitive-behavioral and motivational enhancement therapy may be useful for treatment of marijuana dependence and relapse prevention for cannabis use.
State of the art treatments for cannabis dependence.
- Psychology, MedicineThe Psychiatric clinics of North America
- 2012
Progress toward pharmacotherapies for cannabis-use disorder: an evidence-based review
- Medicine, PsychologySubstance abuse and rehabilitation
- 2016
Evidence has shown a decrease in the age of commencement of cannabis use in some developed countries and a prolongation of risk of initiation to cannabis use beyond adolescence among more recent users.
Lithium carbonate in the management of cannabis withdrawal in humans: an open-label study
- Psychology, MedicineJournal of psychopharmacology
- 2009
Evidence is provided for the potential clinical utility and safety of lithium in the management of cannabis withdrawal in treatment seeking adult humans and a randomised, placebo-controlled trial is recommended.
Cannabis Withdrawal: a Review of Neurobiological Mechanisms and Sex Differences
- Biology, MedicineCurrent Addiction Reports
- 2017
Pre-clinical and clinical research on the etiology and biological substrates of the cannabis withdrawal syndrome are provided, and females have been shown to have increased rate and severity of a subset of cannabis withdrawal symptoms compared with men.
Cannabis use, abuse, and withdrawal: Cannabinergic mechanisms, clinical, and preclinical findings
- Biology, PsychologyJournal of neurochemistry
- 2021
This narrative review aims to summarize major research elucidating the molecular, cellular, and behavioral manifestations of cannabis/THC use that play a role in cannabis use disorder and withdrawal.
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