The canine 'groove' model of osteoarthritis is more than simply the expression of surgically applied damage.

@article{Mastbergen2006TheC,
  title={The canine 'groove' model of osteoarthritis is more than simply the expression of surgically applied damage.},
  author={S C Mastbergen and Anne Carien A Marijnissen and Marieke E Vianen and Peter M van Roermund and Johannes W J Bijlsma Bijlsma and Floris P. J. G. Lafeber},
  journal={Osteoarthritis and cartilage},
  year={2006},
  volume={14 1},
  pages={39-46}
}
OBJECTIVE Recently a new canine model of osteoarthritis (OA; the 'groove' model) has been described. This model is based on surgically applied mechanical damage of the articular cartilage followed by transient forced loading of the affected joint. Ten weeks after surgery this model shows characteristics of OA, mimicking human OA. To establish whether the observed characteristics of degeneration in this model represent the surgically applied damage, or are the results of progressive features of… CONTINUE READING

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