The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis

@article{Garkavtsev2004TheCT,
  title={The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis},
  author={I. Garkavtsev and S. Kozin and O. Chernova and Lei Xu and F. Winkler and E. Brown and G. Barnett and R. Jain},
  journal={Nature},
  year={2004},
  volume={428},
  pages={328-332}
}
Gliomas are the most common primary tumours of the central nervous system, with nearly 15,000 diagnosed annually in the United States and a lethality approaching 80% within the first year of glioblastoma diagnosis. The marked induction of angiogenesis in glioblastomas suggests that it is a necessary part of malignant progression; however, the precise molecular mechanisms underlying the regulation of brain tumour growth and angiogenesis remain unresolved. Here we report that a candidate tumour… Expand
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