The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

@article{Cooper2007TheCG,
  title={The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes},
  author={Jason. D Cooper and Deborah J. Smyth and Rebecca Kim Min-Ae Bailey and Felicity Payne and Kate Downes and Lisa M Godfrey and Jennifer Masters and Lauren R Zeitels and Adrian Vella and Neil M. Walker and John A. Todd},
  journal={BMC Medical Genetics},
  year={2007},
  volume={8},
  pages={71 - 71}
}
As genes associated with immune-mediated diseases have an increased prior probability of being associated with other immune-mediated diseases, we tested three such genes, IL23R , IRF5 and CD40 , for an association with type 1 diabetes. In addition, we tested seven genes, TAF5L , PDCD1, TCF7, IL12B , IL6 , ICAM1 and TBX21 , with published marginal or inconsistent evidence of an association with type 1 diabetes. We genotyped reported polymorphisms of the ten genes, nonsynonymous SNPs (nsSNPs) and… CONTINUE READING

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