The cancer drug imatinib can cause cardiotoxicity

  • Published 2007 in Nature Clinical Practice Cardiovascular Medicine

Abstract

Imatinib mesylate is a tyrosine kinase inhibitor used in the treatment of cancers including chronic myeloid leukemia. In their study, however, Kerkelä et al. report that this drug can be cardiotoxic, causing severe left ventricular dysfunction and heart failure in occasional patients. The authors studied 10 individuals who, having had no previous history of… (More)
DOI: 10.1038/ncpcardio0699

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