The cancer cachexia syndrome.

@article{Fearon2001TheCC,
  title={The cancer cachexia syndrome.},
  author={K. C. Fearon and Matthew D Barber and Alastair G. W. Moses},
  journal={Surgical oncology clinics of North America},
  year={2001},
  volume={10 1},
  pages={109-26}
}
The provision of additional calories and protein alone has not been shown to be efficacious in patients with cancer cachexia. Although primary research continues to unravel the complex metabolic derangements and diverse mediator pathways underlying cancer cachexia, the future lies in drugs and neutracenticals that may modulate this altered metabolism and enable conventional nutritional support to effectively replenish vital lean tissue. 

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