The calcium deficiency hypothesis of hypertension: a critique.

  title={The calcium deficiency hypothesis of hypertension: a critique.},
  author={Norman M. Kaplan and R B Meese},
  journal={Annals of internal medicine},
  volume={105 6},
Primary (essential) hypertension has recently been related to calcium deficiency, rather than excess. The evidence used to support this hypothesis includes surveys showing lesser dietary intake of calcium, lower levels of ionized calcium in the blood, and reduction of blood pressure with calcium supplements. This critique examines each of these points and the theoretical construct used to explain the hypothesis. We conclude that the theoretical construct is based on the use of only a portion of… CONTINUE READING