The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats.

Abstract

Calcimimetics and vitamin D sterols reduce serum parathyroid hormone (PTH) in patients with secondary hyperparathyroidism receiving dialysis, a disease state associated with parathyroid hyperplasia, vascular calcification, bone disease, and increased mortality. The aim of this study was to determine the effects of the research calcimimetic AMG 641 (Amgen… (More)
DOI: 10.1016/j.ejphar.2009.05.013

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Cite this paper

@article{Henley2009TheCA, title={The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats.}, author={Charles M. Henley and James H Davis and Gerald Miller and Edward M Shatzen and Russ C Cattley and Xiaodong Li and David E. Martin and Wei Yao and Nancy E. Lane and Victoria Shalhoub}, journal={European journal of pharmacology}, year={2009}, volume={616 1-3}, pages={306-13} }