The caffeoylics as a new family of natural antiviral compounds

  title={The caffeoylics as a new family of natural antiviral compounds},
  author={B. K{\"o}nig and J. H. Dustmann},
Considering some of the best-known reviews on antiviral chemotherapy [i-3], there has been on the one hand an obvious increase in knowledge both of antivirotically active compounds and of modes of action, but on the other hand, this increase in knowledge is relatively sparse compared to the development of antimicrobial chemotherapy. In fact, in broad areas of viral diseases there is currently no effective chemotherapy at hand, and in many cases no kind of therapy at all, as is reported in many… 
How do bees prevent hive infections? The antimicrobial properties of propolis
The current knowledge about propolis diversity (geographic, compositional), its biological activities with emphasis to antimicrobial activity, and its potential therapeutic applications are reviewed.
Antiviral activities of flavonoids isolated from the bark of Rhus verniciflua stokes against fish pathogenic viruses In Vitro
Results suggested that the bark of R. verniciflua and isolated flavonoids have significant anti-viral activity against IHNV and VHSV, and also have potential to be used as anti-Viral therapeutics against fish viral diseases.
Phytochemistry and pharmacology of the genus pedicularis used in traditional Chinese medicine.
In vitro and in vivo studies indicated some monomer compounds and extracts from the genus Pedicularis have been found to possess antitumor, hepatoprotective, anti-oxidative, antihaemolysis, antibacterial activity, fatigue relief of skeletal muscle, nootropic effect and other activities.
Antileishmanial Lead Structures from Nature: Analysis of Structure-Activity Relationships of a Compound Library Derived from Caffeic Acid Bornyl Ester
The Michael system seems not to be essential for antileishmanial activity, and compound 27 can be regarded as new lead structure for further structure optimization.
An in vitro study on antimicrobial activity of propolis from Mugla province of Turkey.
A control test run with standard antibiotics revealed that propolis samples from the Mugla province of Turkey has a similar or greater inhibitory effect on S. mutans, Salmonella typhi, Pseudomonas aeruginosa, S. sonnei, and C. albicans growth.
Determination of Phenylpropanoid Glycosides in Chinese Herbal Extracts from Pedicularis Species by HPLC
Abstract A simple, rapid, and accurate high performance liquid chromatographic (HPLC) technique coupled with photodiode array (PDA) detection was developed for the simultaneous determination of three
Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities.
The aporphine alkaloid glaucine has been converted into 3-aminomethylglaucine and its free amino group has been linked to cinnamic, ferulic, sinapic, o-, and p-coumaric acids, and the newly synthesized compounds were tested in vitro for antiviral activity against viruses belonging to different taxonomic groups.
Caffeoylquinic acids as inhibitors for HIV-I protease and HIV-I Integrase. A Molecular docking study
Caffeoylquinic acids are ubiquitous phenolic compounds with several health benefits to humans and they have been shown to be promisinganti-HIV compounds. In this work, molecular docking was used to
Amtimicrobial activity of essential oil of Melissa officinalis L, Lamiaceae
The antimicrobial activity of the essential oil of Melissa officinalis was investigated in this paper. The essential oil was obtained by the principle of water and steam and analyzed by GC and GC-MS
Propolis: Composition, Health, Medicine: A Review
The Roman scholar Plinius (23-79 A.D) postulated, t hat it originates in the buds of different trees li ke willow, poplar, elm, reed and other plants. He kn w of the use of propolis as a glue in the


Antiviral Substances in Plants of the Mint Family (Labiatae). II. Nontannin Polyphenol of Melissa officinalis. ∗
  • E. C. Herrmann, L. Kucera
  • Biology, Medicine
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1967
Summary The presence of gelatin did not eliminate the antiviral activity of aqueous extracts of Melissa officinalis against herpes simplex and vaccinia viruses in disc plaque-suppression tests,
Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate.
Extracts of samples of a Caribbean tunicate of the family Didemnidae inhibit in vitro at low concentrations the growth of DNA and RNA viruses as well as L1210 leukemic cells.
Polymere Hilfsstoffe in der pharmazeutischen Technologie
  • K. Bauer
  • Chemistry
  • 2005
Based on their outstanding properties, polymeric materials have conquered in pharmaceutical technology a broad field of application from solid dosage forms to liquids. These attributes reach from
Antiviral Agents and Viral Diseases of Man
For antiherpetic activity of propolis see : Crisan , I . , et al . : II . Apitherapie Symposium Bukarest 1976 , p . 184 . Bukarest : Apimondia 1976
  • Hand - book of Experimental Pharmacology
  • 1982
eds): Chemotherapy of Viral Infections
  • Handbook of Experimental Pharmacology,
  • 1982
Antiviral Drugs. Basel: Karger t 976; Mfiller, W.E.G., Zahn, R.K.: Biochemistry of Antivirals
  • Curr. Top. Microbiol. Immun
  • 1978
For antiherpetic activity of propolis
  • II. Apitherapie Symposium Bukarest
  • 1976
For antiviral effects of flavonoids
  • Proc. AACR and ASCO 16,
  • 1975
Chemotherapy of viral infections.