The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa.

@article{Feng1998TheCR,
  title={The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa.},
  author={Huai L. Feng and Jay I. Sandlow and Alexander Sandra},
  journal={Molecular reproduction and development},
  year={1998},
  volume={49 3},
  pages={317-26}
}
The presence and role of the c-kit protein was investigated in the mature sperm of the mouse. The c-kit monoclonal antibody (mAb) ACK2 reacted specifically with the acrosomal region and the principal piece of fixed noncapacitated sperm but did not react with the acrosome region in acrosome-reacted sperm. ACK2 significantly inhibited the acrosome reaction… CONTINUE READING