The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

@article{Sherr1985TheCP,
  title={The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1},
  author={C. Sherr and C. W. Rettenmier and R. Sacca and M. Roussel and E. R. Stanley},
  journal={Cell},
  year={1985},
  volume={41},
  pages={665-676}
}
  • C. Sherr, C. W. Rettenmier, +2 authors E. R. Stanley
  • Published 1985
  • Biology, Medicine
  • Cell
  • The feline c-fms proto-oncogene product is a 170 kd glycoprotein with associated tyrosine kinase activity. This glycoprotein was expressed on mature cat macrophages from peritoneal inflammatory exudates and spleen. Similarly, the receptor for the murine colony-stimulating factor, CSF-1, is restricted to cells of the mononuclear phagocytic lineage and is a 165 kd glycoprotein with an associated tyrosine kinase. Rabbit antisera to a recombinant v-fms-coded polypeptide precipitated the feline c… CONTINUE READING
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