The c-Fes protein-tyrosine kinase accelerates NGF-induced differentiation of PC12 cells through a PI3K-dependent mechanism.

Abstract

The c-fes protooncogene encodes a non-receptor protein-tyrosine kinase (Fes) that has been implicated in the differentiation of myeloid haematopoietic cells. Fes is also expressed in several neuronal cell types and the vascular endothelium, suggestive of a more general function in development. To examine the role of Fes in neuronal differentiation, we… (More)

Topics

Cite this paper

@article{Shibata2003TheCP, title={The c-Fes protein-tyrosine kinase accelerates NGF-induced differentiation of PC12 cells through a PI3K-dependent mechanism.}, author={Annemarie Shibata and Charles E Laurent and Thomas E Smithgall}, journal={Cellular signalling}, year={2003}, volume={15 3}, pages={279-88} }