The burden of illness of irritable bowel syndrome: current challenges and hope for the future.

@article{Hulisz2004TheBO,
  title={The burden of illness of irritable bowel syndrome: current challenges and hope for the future.},
  author={Darrell T. Hulisz},
  journal={Journal of managed care pharmacy : JMCP},
  year={2004},
  volume={10 4},
  pages={
          299-309
        }
}
  • D. Hulisz
  • Published 1 July 2004
  • Medicine
  • Journal of managed care pharmacy : JMCP
OBJECTIVES To review unmet medical needs associated with irritable bowel syndrome (IBS), to discuss factors that contribute to these unmet needs, and to provide an overview of advancements in IBS diagnosis and treatment options that may influence treatment strategies. SUMMARY IBS is characterized by a multiple symptom complex of abdominal pain or discomfort and altered bowel habits (i.e., constipation, diarrhea, or both in alternation) and is associated with a large unmet medical need. IBS… 
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Multidimensionality of symptom complexes in irritable bowel syndrome and other functional gastrointestinal disorders.
  • D. Alpers
  • Medicine
    Journal of psychosomatic research
  • 2008
TLDR
This article proposes that the definitions of IBS or other FGIDs not be altered, but that in the process of evaluation of the clinical end points and/or severity of the diseases, consideration be given to the possibility of including other components of the symptom burden of these disorders.
Economic Burden of Irritable Bowel Syndrome with Diarrhea: Retrospective Analysis of a U.S. Commercially Insured Population.
TLDR
IBS-D was associated with a substantial burden in direct costs in this population of commercially insured patients and incurred significantly more annual all-cause health care costs, even after controlling for demographics and comorbidities.
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