The burden of constipation on quality of life: results of a multinational survey

  title={The burden of constipation on quality of life: results of a multinational survey},
  author={Arnold Wald and Carmelo Scarpignato and M. A. Kamm and Stefan A. Mueller-Lissner and I Helfrich and Chris Schuijt and Juergen Bubeck and Costanzo Limoni and Orlando Petrini},
  journal={Alimentary Pharmacology \& Therapeutics},
Background The impact of constipation on quality of life (QoL) may vary in different cultural or national settings. 

Levels of satisfaction with current chronic constipation treatment options in Europe – an internet survey

Data on treatment satisfaction in European men and women with chronic constipation is limited and the need for further research is needed to establish a baseline for treatment satisfaction.

Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation – a 12‐week, randomized, double‐blind, placebo‐controlled study

This study focuses on the treatment of chronic constipation in women with a history of diarrhea and its role in the quality of life.

Cross cultural comparison of constipation profiles at tertiary care centers between India and USA

  • P. SinghR. Surana B. Kuo
  • Medicine
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2018
Despite potential differences in patient perception of chronic constipation (CC) in geographically and culturally distinct regions, head‐to‐head studies comparing the clinical profile, constipation

Impact of chronic constipation on health‐related quality of life and work productivity in Japan

This study aimed to evaluate and compare the humanistic burden of respondents with chronic constipation to respondents without Chronic constipation and to respondents with type 2 diabetes mellitus, irritable bowel syndrome, and gastroesophageal reflux disease (GERD), respectively.

Systematic review: impact of constipation on quality of life in adults and children

Aliment Pharmacol Ther 31, 938–949

Interferential therapy: a new treatment for slow transit constipation. A pilot study in adults

The study aimed to assess, for the first time, the effectiveness of interferential therapy (IFT) in the treatment of slow transit constipation in adults and its impact on the quality of life.

The impact of abdominal pain on global measures in patients with chronic idiopathic constipation, before and after treatment with linaclotide: a pooled analysis of two randomised, double-blind, placebo-controlled, phase 3 trials

Few clinical trials in chronic idiopathic constipation (CIC) patients have evaluated abdominal symptom severity and whether CIC patients with abdominal symptoms respond similarly to patients with

The Pharmacological Management of Chronic Constipation and Faecal Incontinence

This two part chapter describes the use of pharmacotherapy in the management of bowel dysfunction and provides the reader with an insight into possible treatment options.

Prevalence and risk factors of functional constipation in the Rome IV criteria during a medical check‐up in Japan

Examination of the epidemiology of FC in a large‐scale survey of individuals undergoing a medical check‐up in Japan found no significant differences between men and women with and without symptoms of constipation.

Function and clinical implications of short‐chain fatty acids in patients with mixed refractory constipation

  • Y. ShiQ. Chen N. Li
  • Medicine
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • 2016
The present study was designed to investigate the function and clinical implications of stool short‐chain fatty acids (SCFAs) in patients with mixed refractory constipation.



A new questionnaire for constipation and faecal incontinence

The prevalence, severity and risk factors of faecal incontinence in women in the community are incompletely characterized and the need for further research into these factors and their role in women's sexual activity is unclear.

Application of the general health status questionnaire SF36 to patients with gastrointestinal dysfunction: initial validation and validation as a measure of change

Objective : To determine whether the Short Form (SF36) Health Status Survey is a valid measure of health status and health change for patients with irritable bowel syndrome (IBS).

Impact of anal incontinence and chronic constipation on quality of life.

Psychological state and quality of life in patients having behavioral treatment (biofeedback) for intractable constipation

The symptomatic improvement produced by biofeedback in constipated patients is associated with improved psychological state andQOL, and QOL parameters may be useful for predicting a likely response to treatment.

Epidemiology of constipation (EPOC) study in the United States: relation of clinical subtypes to sociodemographic features

Differences in epidemiological profile by age, sex ratio, and relation to other sociodemographical factors support the distinction of two and possibly more symptom-based subtypes of constipation.

Is Constipation Associated with Decreased Physical Activity in Normally Active Subjects?

Physical activity appears to be unrelated to the risk of constipation in employed adults, but higher physical activity was associated with improved QoL, and recommendations to increase physical activity may not alter symptoms ofconstipation but may improve overall well-being.

Quality of life in patients with irritable bowel syndrome seen in referral centers versus primary care: the impact of gender and predominant bowel pattern.

IBS female patients seen in referral centers versus primary care is a highly selected group with reduced QOL, affected by gender, but not by subgroup, which has implications for the generalizability of results in IBS trials.

Quality of life instruments in studies of chronic pelvic pain: a systematic review

There is a need to develop disease specific QoL instruments for CPP with face validity in addition to sound measurement properties, and compliance with the quality criteria for measurement properties is higher than for clinical face validity.

Definitions, epidemiology, and impact of chronic constipation.

  • N. Talley
  • Medicine
    Reviews in gastroenterological disorders
  • 2004
There is accumulating evidence that self-reported constipation and functional constipation as defined by the Rome Criteria lead to significant impairment of quality of life, with the implication that this is a serious condition in the majority of people afflicted.

Geographic Distribution of Constipation in the United States

  • J. Johanson
  • Medicine
    American Journal of Gastroenterology
  • 1998
The distinct geographic pattern of constipation suggests the influence of three global environmental factors: rural living, colder temperature, and lower socioeconomic status.