The bulk of the phosphorylation of human respiratory syncytial virus phosphoprotein is not essential but modulates viral RNA transcription and replication.

@article{Villanueva2000TheBO,
  title={The bulk of the phosphorylation of human respiratory syncytial virus phosphoprotein is not essential but modulates viral RNA transcription and replication.},
  author={Nieves Villanueva and Richard W Hardy and Ana Teresa Carmona Asenjo and Qian-chun Yu and G T Wertz},
  journal={The Journal of general virology},
  year={2000},
  volume={81 Pt 1},
  pages={129-33}
}
The ability of variants of the human respiratory syncytial virus (HRSV) phosphoprotein (P protein) to support RNA transcription and replication has been studied by using HRSV-based subgenomic replicons. The serine residues normally phosphorylated in P during HRSV infection have been replaced by other residues. The results indicate that the bulk of phosphorylation of P (98%) is not essential for viral RNA transcription or replication but that phosphorylation can modulate these processes. 

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