The brain mineralocorticoid receptor and stress resilience

@article{Heegde2015TheBM,
  title={The brain mineralocorticoid receptor and stress resilience},
  author={F. Ter Heegde and Roel H. de Rijk and Christiaan H. Vinkers},
  journal={Psychoneuroendocrinology},
  year={2015},
  volume={52},
  pages={92-110}
}
Stress exposure activates the HPA-axis and results in the release of corticosteroids which bind to two receptor types in the brain: the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR). While the role of the GR in stress reactivity has been extensively studied, the MR has received less attention. Nevertheless, pioneering in-depth studies over the past two decades have shown the importance of the brain MR in the processing of stressful information. Moreover, a membrane-bound… Expand
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