The brain metabolic enhancer methylene blue improves discrimination learning in rats.

@article{Wrubel2007TheBM,
  title={The brain metabolic enhancer methylene blue improves discrimination learning in rats.},
  author={Kathryn M Wrubel and Penny D. Riha and M{\'o}nica Alexandra Arias Maldonado and David McCollum and F. Gonzalez-Lima},
  journal={Pharmacology, biochemistry, and behavior},
  year={2007},
  volume={86 4},
  pages={712-7}
}
Methylene blue (MB) is a metabolic enhancer that has been demonstrated to improve memory retention when given post-training in low doses in a variety of tasks in rats, including inhibitory avoidance, spatial memory (in both normal and metabolically-impaired subjects), object recognition, and habituation to a familiar environment. MB has been also shown to improve memory retention of extinction of fear conditioning in the rat. No experiments have been conducted to determine the effects of MB on… CONTINUE READING

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