The brain-derived neurotrophic factor gene as a possible susceptibility candidate for Alzheimer's disease in a chinese population.

@article{Tsai2006TheBN,
  title={The brain-derived neurotrophic factor gene as a possible susceptibility candidate for Alzheimer's disease in a chinese population.},
  author={Shih-Jen Tsai and C N Hong and Hsiu-Chih Liu and Tsung-Yun Liu and Ying-Jay Liou},
  journal={Dementia and geriatric cognitive disorders},
  year={2006},
  volume={21 3},
  pages={139-43}
}
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, may represent a candidate gene conferring susceptibility to Alzheimer's disease (AD). This is because it has an important role in neuronal survival, and a decreased central level of BDNF is observed in AD. Some previous studies, though not all, have demonstrated that BDNF C270T polymorphisms might be associated with AD susceptibility. We examined the association of the C270T polymorphisms with sporadic AD in a… CONTINUE READING

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