The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill

Amy L Cilia La Corte; A. Carter; A. Turner; P. J. Grant; N. Hooper

DOI:10.1177/1470320308096405

Corpus ID: 206729914

The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill

@article{Corte2008TheBA,
  title={The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill},
  author={Amy L Cilia La Corte and A. Carter and A. Turner and P. J. Grant and N. Hooper},
  journal={Journal of the Renin-Angiotensin-Aldosterone System},
  year={2008},
  volume={9},
  pages={221 - 225}
}

Amy L Cilia La Corte, A. Carter, +2 authors N. Hooper

Published 2008

Medicine

Journal of the Renin-Angiotensin-Aldosterone System

Introduction. The renin-angiotensin and kininogen-kinin hormonal systems are critically involved in regulating blood pressure and are candidates in contributing to oral contraceptive pill (OCP)-induced hypertension.Angiotensin-converting enzyme (ACE) and aminopeptidase P (AP-P) are key enzymes in these systems and are both involved in the degradation of the vasodilator bradykinin. Methods. Circulating ACE and AP-P levels were measured by activity assay using selective fluorogenic peptide… CONTINUE READING

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