The bradykinin B1 receptor regulates Aβ deposition and neuroinflammation in Tg-SwDI mice.


The deposition of amyloid-β peptides (Aβ) in the cerebral vasculature, a condition known as cerebral amyloid angiopathy, is increasingly recognized as an important component leading to intracerebral hemorrhage, neuroinflammation, and cognitive impairment in Alzheimer disease (AD) and related disorders. Recent studies demonstrated a role for the bradykinin… (More)
DOI: 10.1016/j.ajpath.2013.01.021


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