The bowel and beyond: the enteric nervous system in neurological disorders

@article{Rao2016TheBA,
  title={The bowel and beyond: the enteric nervous system in neurological disorders},
  author={Meenakshi Rao and Michael David Gershon},
  journal={Nature Reviews Gastroenterology &Hepatology},
  year={2016},
  volume={13},
  pages={517-528}
}
The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate gastrointestinal behaviour independently of the central nervous system (CNS). An intact ENS is essential for life and ENS dysfunction is often linked to digestive disorders. The part the ENS plays in neurological disorders, as a portal or participant, has also become increasingly evident. ENS structure and neurochemistry resemble that of the CNS, therefore pathogenic mechanisms that give rise to CNS disorders… CONTINUE READING