The bovine chromogranin A gene: structural basis for hormone regulation and generation of biologically active peptides.

Abstract

The structure of the gene encoding bovine chromogranin-A has been determined by characterization of two isolated genomic clones. Chromogranin-A is encoded by eight exons, which organize the coding region into several distinct structural and functional domains. Exons 1-5 represent the highly conserved signal peptide and N-terminal domain, which are separated… (More)

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Cite this paper

@article{Iacangelo1991TheBC, title={The bovine chromogranin A gene: structural basis for hormone regulation and generation of biologically active peptides.}, author={Abigail Iacangelo and M. Grimes and Laura Eiden}, journal={Molecular endocrinology}, year={1991}, volume={5 11}, pages={1651-60} }