The bone marrow histological pattern has independent prognostic value in early stage chronic lymphocytic leukaemia.

@article{Geisler1986TheBM,
  title={The bone marrow histological pattern has independent prognostic value in early stage chronic lymphocytic leukaemia.},
  author={Christian Hartman Geisler and Elisabeth Methner Ralfkiaer and Mogens M\ork Hansen and Klaus Hou-Jensen and Severin Olesen Larsen},
  journal={British journal of haematology},
  year={1986},
  volume={62 1},
  pages={47-54}
}
The initial diagnostic bone marrow specimens from 90 consecutive, untreated patients with chronic lymphocytic leukaemia were examined for the pattern of lymphocytic infiltration in relation to clinical stage (International Workshop System) and survival. Three non-diffuse (interstitial, nodular, mixed nodular-interstitial) and one diffuse pattern were… CONTINUE READING