The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery.

@article{Breuer2009TheBS,
  title={The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery.},
  author={Tam{\'a}s Breuer and Klaus Daniel Martin and Markus J. Wilhelm and Gunther Wiesner and Christian Schreiber and John Hess and Ruediger Lange and Peter Tassani},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2009},
  volume={35 1},
  pages={167-71; author reply 171}
}
OBJECTIVE Recently, the safety of aprotinin administration during open-heart surgery has been debated. The aim of the study was to compare the blood sparing effect and the side effects of aprotinin and tranexamic acid in paediatric cardiac surgery patients. METHODS Perioperative data of 199 consecutive patients weighing less than 20kg undergoing open-heart cardiac surgery were prospectively collected between September 2005 and June 2006. During the first 5 months, 85 patients received… CONTINUE READING
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