The blood-brain barrier in hypoxia: ultrastructural aspects and adenylate cyclase activity of brain capillaries.

@article{Dux1984TheBB,
  title={The blood-brain barrier in hypoxia: ultrastructural aspects and adenylate cyclase activity of brain capillaries.},
  author={Emma L Dux and P{\'e}ter Temesv{\'a}ri and Ferenc Jo{\'o} and G{\'e}za {\'A}d{\'a}m and Francesco Clementi and L{\'a}szl{\'o} Dux and J. Hideg and K. A. Hossmann},
  journal={Neuroscience},
  year={1984},
  volume={12 3},
  pages={951-8}
}
The ultrastructure of brain microvessels, their permeability to serum albumin, the activities of some endothelial enzymes and the effect of histamine were investigated in rats after a prolonged hypobaric-hypoxic treatment. After prolonged hypoxia, the permeation of serum albumin into endothelial cells increased together with the number of pinocytotic vesicles of the endothelium. Intracarotid histamine stimulated this process even further, and its effect was mediated by H2-histamine receptors… CONTINUE READING
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