The biosynthetic pathway of vitamin C in higher plants

@article{Wheeler1998TheBP,
  title={The biosynthetic pathway of vitamin C in higher plants},
  author={Glen L Wheeler and Mark A. Jones and Nicholas Smirnoff},
  journal={Nature},
  year={1998},
  volume={393},
  pages={365-369}
}
Vitamin C (L-ascorbic acid) has important antioxidant and metabolic functions in both plants and animals, but humans, and a few other animal species, have lost the capacity to synthesize it. Plant-derived ascorbate is thus the major source of vitamin C in the human diet. Although the biosynthetic pathway of L-ascorbic acid in animals is well understood, the plant pathway has remained unknown—one of the few primary plant metabolic pathways forwhich this is the case. L-ascorbate is abundant in… 
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