The biosynthesis of 5-hydroxytryptamine in brain.

  title={The biosynthesis of 5-hydroxytryptamine in brain.},
  author={David G. Grahame-Smith},
  journal={The Biochemical journal},
  volume={105 1},
1. Studies on the anatomical distribution of tryptophan 5-hydroxylase in dog brain show that the activity of this enzyme parallels the activity of 5-hydroxytryptophan decarboxylase and the concentration of 5-hydroxytryptamine in various areas of the brain. 2. Subcellular fractionation of homogenates of rabbit hind-brain has shown that at least 40% of the… CONTINUE READING