The biology of the platelet with special reference to inflammation, wound healing and immunity.
@article{Nurden2018TheBO, title={The biology of the platelet with special reference to inflammation, wound healing and immunity.}, author={Alan T Nurden}, journal={Frontiers in bioscience}, year={2018}, volume={23}, pages={ 726-751 } }
While platelets have long been known to be essential for maintaining hemostasis in the vasculature, their role in tissue repair, inflammation and innate and adaptive immunity is a more recent science. The ability of platelets to attach to the vessel wall, form aggregates and promote fibrin formation, key elements of blood clotting, has been said to both favor and dampen inflammation, to fight infection and to assure an adequate immune response. To fulfill their different roles platelets often…
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