The biology of neurotrophins, signalling pathways, and functional peptide mimetics of neurotrophins and their receptors.

@article{Skaper2008TheBO,
  title={The biology of neurotrophins, signalling pathways, and functional peptide mimetics of neurotrophins and their receptors.},
  author={Stephen D Skaper},
  journal={CNS & neurological disorders drug targets},
  year={2008},
  volume={7 1},
  pages={46-62}
}
The neurotrophins are a family of closely related proteins that were first identified as survival factors for sympathetic and sensory neurons, and have since been shown to control a number of aspects of survival, development and function of neurons in both the central and peripheral nervous systems. Limiting quantities of neurotrophins during development control the numbers of surviving neurons to ensure a match between neurons and the requirement for a suitable density of target innervation… CONTINUE READING