The biology of interleukin-6.

  title={The biology of interleukin-6.},
  author={Tadamitsu Kishimoto},
  volume={74 1},
B CELLS ARE the only eukaryotic cells that are able to produce antibody molecules. Their growth and differentiation into antibody producing cells require the presence of T cells and macrophages; the function of these cells was found to be replaced by soluble factors. 3 In the early i980s it was shown that at least two different kinds of factors were required in the regulation of B cell response, one for growth of activated B cells, B-cell growth factor (BCGF), and the other for antibody… CONTINUE READING
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