The biology of circulating tumor cells

@article{Pantel2016TheBO,
  title={The biology of circulating tumor cells},
  author={Klaus Pantel and Michael R. Speicher},
  journal={Oncogene},
  year={2016},
  volume={35},
  pages={1216-1224}
}
Metastasis is a biologically complex process consisting of numerous stochastic events which may tremendously differ across various cancer types. Circulating tumor cells (CTCs) are cells that are shed from primary tumors and metastatic deposits into the blood stream. CTCs bear a tremendous potential to improve our understanding of steps involved in the metastatic cascade, starting from intravasation of tumor cells into the circulation until the formation of clinically detectable metastasis… CONTINUE READING

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