The biology behind the atherothrombotic effects of cigarette smoke

@article{Csords2013TheBB,
  title={The biology behind the atherothrombotic effects of cigarette smoke},
  author={Adam Csord{\'a}s and David Bernhard},
  journal={Nature Reviews Cardiology},
  year={2013},
  volume={10},
  pages={219-230}
}
Cigarette smoke is an aerosol that contains >4,000 chemicals, including nicotine, carbon monoxide, acrolein, and oxidant compounds. Exposure to cigarette smoke induces multiple pathological effects in the endothelium, several of which are the result of oxidative stress initiated by reactive oxygen species, reactive nitrogen species, and other oxidant constituents of cigarette smoke. Cigarette-smoke exposure interferes adversely with the control of all stages of plaque formation and development… 

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