The biology and enzymology of protein N-myristoylation.

  title={The biology and enzymology of protein N-myristoylation.},
  author={Thalia A. Farazi and Gabriel Waksman and J. I. Gordon},
  journal={The Journal of biological chemistry},
  volume={276 43},
Protein N-myristoylation refers to the covalent attachment of myristate, a 14-carbon saturated fatty acid, to the N-terminal glycine of eukaryotic and viral proteins. N-Myristoylproteins have diverse functions and intracellular destinations. They include proteins involved in a wide variety of signal transduction cascades. In general, N-myristoylation is an… CONTINUE READING